Linker Phosphoramidites
5'-Thiol-Modifier C6
Quick view. 5'-Thiol-Modifier C6 is an S-trityl-protected C6 thiol phosphoramidite identified by CAS 116919-17-6 for oligonucleotide synthesis research. CAS 116919-17-6. Catalog target purity: ≥98%. Availability: Inquiry only; contact BX Lab to confirm current availability.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5'-Thiol-Modifier C6 is classified as linker phosphoramidites (Formula C34H45N2O2PS; molecular weight 576.78).
5'-Thiol-Modifier C6 — Reference use: introduction of a protected C6 thiol functionality at the 5' terminus during oligonucleotide synthesis.
For 5'-Thiol-Modifier C6, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 5'-Thiol-Modifier C6 CE-Phosphoramidite
- Trityl-6-Thiohexyl Amidite
- 2-cyanoethyl (6-(tritylthio)hexyl) diisopropylphosphoramidite
Useful catalog search terms
- CAS 116919-17-6
- C34H45N2O2PS
Physicochemical data
| Systematic-name reference | 2-cyanoethyl (6-(tritylthio)hexyl) diisopropylphosphoramidite |
|---|---|
| Product-form boundary | Distinct from Thiol-Modifier C6 S-S (CAS 148254-21-1) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-Thiol-Modifier C6 or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-Thiol-Modifier C6 be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-LP-0038 and CAS 116919-17-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Linker Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.