2'-FANA Nucleosides
6-Amino-2-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)arabinoriboside
Quick view. A 2'-F-ANA nucleoside bearing a 2-chloro-6-aminopurine base and free 3' and 5' hydroxyl groups, CAS 123318-82-1. CAS 123318-82-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
6-Amino-2-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)arabinoriboside is classified as 2'-fana nucleosides (Formula C10H11ClFN5O3; molecular weight 303.68).
6-Amino-2-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)arabinoriboside provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 6-Amino-2-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)arabinoriboside, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- Clofarabine
- CAFdA
- GL100565
Useful catalog search terms
- CAS 123318-82-1
- PubChem CID 119182
Physicochemical data
| PubChem CID | 119182 |
|---|---|
| InChIKey | WDDPHFBMKLOVOX-AYQXTPAHSA-N |
| SMILES | C1=NC2=C(N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)N=C(N=C2N)Cl |
| Base substitution | 2-chloro; 6-amino |
| Sugar configuration | beta-D-2'-deoxy-2'-fluoroarabinofuranose |
| Hydroxyl state | 3' and 5' hydroxyl groups unprotected |
| InChI | InChI=1S/C10H11ClFN5O3/c11-10-15-7(13)5-8(16-10)17(2-14-5)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4+,6-,9-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 6-Amino-2-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)arabinoriboside or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2'-FANA-dG
2'-FANA Nucleosides · CAS: 103884-98-6
BX-MN-01622'-FANA-dC
2'-FANA Nucleosides · CAS: 56632-83-8
BX-MN-01632'-FANA-dT
2'-FANA Nucleosides · CAS: 69256-17-3
BX-MN-01722'-Deoxy-2'-fluoro-beta-D-arabinouridine
2'-FANA Nucleosides · CAS: 69123-94-0
BX-2FAN-00012'-Deoxy-2'-fluoro-beta-D-arabino-2-thiouridine
2'-FANA Nucleosides · CAS: 1006872-85-0
BX-2FAN-00042-Aminopurine-9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside
2'-FANA Nucleosides · CAS: 109304-04-3
Frequently asked questions
Can the package size for 6-Amino-2-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)arabinoriboside be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FAN-0012 and CAS 123318-82-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.