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Sulfurizing Reagents

Beaucage Reagent

Quick view. A benzodithiole sulfur-transfer reagent used in the sulfurization step for phosphorothioate oligonucleotide synthesis. CAS 66304-01-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Chemical structure of Beaucage reagent
Chemical structure
Catalog numberBX-SR-0003
CAS number66304-01-6
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

Beaucage Reagent is classified as sulfurizing reagents (Formula C7H4O3S2; molecular weight 200.23).

Typical application

Beaucage Reagent — Sulfurization step for formation of phosphorothioate linkages in oligonucleotide synthesis workflows.

Handling focus

For Beaucage Reagent, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

PubChem CID3009847
InChIKeyJUDOLRSMWHVKGX-UHFFFAOYSA-N
Systematic name3H-1,2-Benzodithiol-3-one 1,1-dioxide
Reagent classBenzodithiole sulfur-transfer reagent
InChIInChI=1S/C7H4O3S2/c8-7-5-3-1-2-4-6(5)12(9,10)11-7/h1-4H
SMILESC1=CC=C2C(=C1)C(=O)SS2(=O)=O

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Frequently asked questions

Can the package size for Beaucage Reagent be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-SR-0003 and CAS 66304-01-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-relevant literature

The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.