Sulfurizing Reagents
Beaucage Reagent
Quick view. A benzodithiole sulfur-transfer reagent used in the sulfurization step for phosphorothioate oligonucleotide synthesis. CAS 66304-01-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Product profile
Beaucage Reagent is classified as sulfurizing reagents (Formula C7H4O3S2; molecular weight 200.23).
Beaucage Reagent — Sulfurization step for formation of phosphorothioate linkages in oligonucleotide synthesis workflows.
For Beaucage Reagent, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3H-1,2-Benzodithiol-3-one 1,1-dioxide
- 3H-Benzo[c][1,2]dithiol-3-one 1,1-dioxide
Useful catalog search terms
- CAS 66304-01-6
- PubChem CID 3009847
Physicochemical data
| PubChem CID | 3009847 |
|---|---|
| InChIKey | JUDOLRSMWHVKGX-UHFFFAOYSA-N |
| Systematic name | 3H-1,2-Benzodithiol-3-one 1,1-dioxide |
| Reagent class | Benzodithiole sulfur-transfer reagent |
| InChI | InChI=1S/C7H4O3S2/c8-7-5-3-1-2-4-6(5)12(9,10)11-7/h1-4H |
| SMILES | C1=CC=C2C(=C1)C(=O)SS2(=O)=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for Beaucage Reagent be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SR-0003 and CAS 66304-01-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.
