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RNA (2'-O-TBDMS) Phosphoramidites

DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite

Quick view. DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite is an N6-benzoyl- and 2'-O-TBDMS-protected adenosine building block for research-use RNA oligonucleotide synthesis. CAS 104992-55-4. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Chemical structure of DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite
Chemical structure
Catalog numberBX-R2OT-0023
CAS number104992-55-4
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite is classified as protected riboadenosine phosphoramidite (Formula C53H66N7O8PSi; molecular weight 988.20).

Typical application

DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite — N6-benzoyl- and 2'-O-TBDMS-protected adenosine phosphoramidite building block for research-use RNA oligonucleotide synthesis.

Handling focus

For DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

Base protectionN6-benzoyl
Ribose protection2'-O-TBDMS
Synthesis format5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite
InChIKeyFFXHNCNNHASXCT-RFMFGJHUSA-N
InChIInChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1
SMILESCOc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Frequently asked questions

Can the package size for DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-R2OT-0023 and CAS 104992-55-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-family literature

These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.