RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite
Quick view. DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite is an N2-isobutyryl- and 2'-O-TBDMS-protected guanosine building block for research-use RNA oligonucleotide synthesis. CAS 147201-04-5. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite is classified as protected riboguanosine phosphoramidite (Formula C50H68N7O9PSi; molecular weight 970.20).
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite — N2-isobutyryl- and 2'-O-TBDMS-protected guanosine phosphoramidite building block for research-use RNA oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- iBu-rG Phosphoramidite
- DMT-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite
- 2'-O-TBDMS-rG(iBu) Phosphoramidite
Useful catalog search terms
- 147201-04-5
- PubChem 135587729
- C50H68N7O9PSi
- Areterna PA009
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Base protection | N2-isobutyryl |
|---|---|
| Ribose protection | 2'-O-TBDMS |
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | PGJKESPHANLWME-FTZVBZPOSA-N |
| InChI | InChI=1S/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(66-68(12,13)49(7,8)9)42(65-67(63-29-17-28-51)57(33(3)4)34(5)6)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/m1/s1 |
| SMILES | COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(O)nc(NC(=O)C(C)C)nc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
6'-O-DMTr-2'-O-TBDMS-5'-Homo-A(Bz)-3'-CE-Phosphoramidite
RNA (2'-O-TBDMS) Phosphoramidites · CAS: N/A
BX-R2OT-0002DMTr-2'-O-TBDMS-2-S-rU-3'-CE-Phosphoramidite
RNA (2'-O-TBDMS) Phosphoramidites · CAS: N/A
BX-R2OT-0003DMTr-2'-O-TBDMS-5-Cl-rU-3'-CE-Phosphoramidite
RNA (2'-O-TBDMS) Phosphoramidites · CAS: N/A
BX-R2OT-0004DMTr-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite
RNA (2'-O-TBDMS) Phosphoramidites · CAS: 173241-78-6
BX-R2OT-0005DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite
RNA (2'-O-TBDMS) Phosphoramidites · CAS: 771494-03-2
BX-R2OT-0006DMTr-2'-O-TBDMS-N6-Me-N6-phenoxyacetyl-rA-3'-CE-Phosphoramidite
RNA (2'-O-TBDMS) Phosphoramidites · CAS: N/A
Frequently asked questions
Can the package size for DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-R2OT-0024 and CAS 147201-04-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.