GalNAc
GalNAc-NAG-25 Phosphoramidite
Quick view. We supply GalNAc-NAG-25 Phosphoramidite as a tri-GalNAc NAG-25 amidite used for automated synthesis of liver-targeted oligonucleotide conjugates. CAS 2130036-52-9. Catalog target purity: Specification on request.
Product profile
GalNAc-NAG-25 Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
GalNAc-NAG-25 Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For GalNAc-NAG-25 Phosphoramidite, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- GalNAc-NAG-25 CEP
- BX-GALN-0018
- GalNAc-NAG 25
- BX-GALN-0023
Useful catalog search terms
- CAS 2130036-52-9
- Protected oligonucleotide phosphoramidite building block
- GalNAc ligand motif
- phosphoramidite coupling group
- GalNAc ligand, linker or conjugation intermediate
- GalNAc
Physicochemical data
| Key chemistry motifs | GalNAc ligand motif; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe GalNAc-NAG-25 Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for GalNAc-NAG-25 Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GALN-0037 and CAS 2130036-52-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss GalNAc-NAG-25 Phosphoramidite or the named structural feature represented by this product.