Intermediates
Im-2'-OMe-IDP
Quick view. A 2'-O-methylinosine 5'-diphosphate intermediate with terminal phosphoroimidazolide activation. Formula and molecular weight refer to the free acid; the sodium form has unspecified stoichiometry. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
Im-2'-OMe-IDP is classified as intermediates (Formula C14H18N6O10P2; molecular weight 492.28).
Im-2'-OMe-IDP supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For Im-2'-OMe-IDP, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Useful catalog search terms
- 2'-O-methylinosine diphosphate phosphoroimidazolide
Physicochemical data
| CAS status | No CAS assigned in the exact supplier record |
|---|---|
| Modified nucleoside | 2'-O-methylinosine |
| Activation state | 5'-diphosphate with terminal phosphoroimidazolide |
| Salt form | Variable sodium form; exact stoichiometry unspecified |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe Im-2'-OMe-IDP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for Im-2'-OMe-IDP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-INTE-0019, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.