2'-FANA Nucleosides
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-beta-D-arabinocytidine
Quick view. An N4-benzoyl- and 5'-O-dimethoxytrityl-protected 2'-fluoro-beta-D-arabinocytidine intermediate for structure-specific 2'-FANA building-block synthesis. CAS 154771-33-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is classified as 2'-fana nucleosides (Formula C37H34FN3O7; molecular weight 651.70).
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-beta-D-arabinocytidine — Protected 2'-fluoro-beta-D-arabinocytidine intermediate for structure-specific 2'-FANA building-block synthesis and route development.
For N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-beta-D-arabinocytidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- CAS 154771-33-2
- PubChem CID 70700565
Physicochemical data
| PubChem CID | 70700565 |
|---|---|
| InChIKey | RAIBEZUVTIPFOJ-SHERYBNQSA-N |
| IUPAC name | N-[1-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@@H]([C@@H](O4)N5C=CC(=NC5=O)NC(=O)C6=CC=CC=C6)F)O |
| Sugar configuration | 2'-fluoro-beta-D-arabino |
| Protecting groups | N4-benzoyl; 5'-O-dimethoxytrityl |
| InChI | InChI=1S/C37H34FN3O7/c1-45-28-17-13-26(14-18-28)37(25-11-7-4-8-12-25,27-15-19-29(46-2)20-16-27)47-23-30-33(42)32(38)35(48-30)41-22-21-31(40-36(41)44)39-34(43)24-9-5-3-6-10-24/h3-22,30,32-33,35,42H,23H2,1-2H3,(H,39,40,43,44)/t30-,32+,33-,35-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-beta-D-arabinocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-beta-D-arabinocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FAN-0026 and CAS 154771-33-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
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