GalNAc
Peracetylated GalNAc succinimidyl pentanoate
Quick view. Peracetylated GalNAc succinimidyl pentanoate is a protected beta-D-GalNAc pentanoic-acid N-hydroxysuccinimide ester, identified by CAS 1953146-64-9. CAS 1953146-64-9. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
Peracetylated GalNAc succinimidyl pentanoate is classified as galnac (Formula C23H32N2O13; molecular weight 544.51).
Peracetylated GalNAc succinimidyl pentanoate can be used when comparing GalNAc ligand/linker architecture for liver-targeted oligonucleotide conjugation research.
For Peracetylated GalNAc succinimidyl pentanoate, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- Peracetylated beta-D-GalNAc pentanoic acid NHS ester
Useful catalog search terms
- CAS 1953146-64-9
- OVRUOPINRDOPSA-UJGPHIHISA-N
Physicochemical data
| IUPAC name | (2,5-dioxopyrrolidin-1-yl) 5-[(2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxypentanoate |
|---|---|
| InChIKey | OVRUOPINRDOPSA-UJGPHIHISA-N |
| Chemical form | Peracetylated beta-D-GalNAc pentanoic-acid N-hydroxysuccinimide ester |
| InChI | InChI=1S/C23H32N2O13/c1-12(26)24-20-22(36-15(4)29)21(35-14(3)28)16(11-34-13(2)27)37-23(20)33-10-6-5-7-19(32)38-25-17(30)8-9-18(25)31/h16,20-23H,5-11H2,1-4H3,(H,24,26)/t16-,20-,21+,22-,23-/m1/s1 |
| SMILES | CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1OCCCCC(=O)ON2C(=O)CCC2=O)COC(=O)C)OC(=O)C)OC(=O)C |
| Canonical SMILES | CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1OCCCCC(=O)ON2C(=O)CCC2=O)COC(=O)C)OC(=O)C)OC(=O)C |
| PubChem CID | 156724416 |
| Structure representation | Peracetylated beta-D-GalNAc pentanoic-acid N-hydroxysuccinimide ester with five assigned sugar stereocentres |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe Peracetylated GalNAc succinimidyl pentanoate or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for Peracetylated GalNAc succinimidyl pentanoate be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GALN-0011 and CAS 1953146-64-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the GalNAc product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.