Modified Nucleosides
S-Adenosylmethionine (SAM)
Quick view. We supply S-Adenosylmethionine (SAM) as a biological methyl-group donor used in methyltransferase, metabolite and biochemical pathway research. CAS 485-80-3. Catalog target purity: ≥90%.
Product profile
S-Adenosylmethionine (SAM) is classified as nucleoside or protected nucleoside intermediate (Formula C15H23N6O5S; molecular weight 400.45).
S-Adenosylmethionine (SAM) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For S-Adenosylmethionine (SAM), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- S-Adenosylmethionine
- S-Adenosyl-L-methionine
- SAM
- SAMe
- AdoMet
- Active methionine
- S-(5'-Adenosyl)methionine
- 5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine
Useful catalog search terms
- CAS 485-80-3
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| Molecular formula (parent zwitterion) | C15H22N6O5S |
|---|---|
| Molecular weight (parent zwitterion) | 398.4 g/mol |
| Supplied form | Confirm counterion or stabilization system, hydration and assay basis before use |
| Identity note | The parent SAM identity is shown; no separate counterion is claimed for this listing |
| InChI | InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7-,8+,10+,11+,14+,27?/m0/s |
| InChIKey | QOWKLNSTGYYNGX-MDHPBGAINA-N |
| SMILES | C(O)(=O)[C@H](CCS(C[C@H]1O[C@@H](N2C3=C(C(=NC=N3)N)N=C2)[C@H](O)[C@@H]1O)C)N |&1:3,8,10,21,23,r| |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
(S)-cEt-rA
Modified Nucleosides · CAS: 1197033-34-3
BX-MN-0185(R-/S-) 5-Carbamoylhydroxy methyluridine
Modified Nucleosides · CAS: N/A
BX-MN-0186(R-/S-)5-(1-Hydroxy)(methoxycarbonyl)methyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0187(R-/S-)5-Carboxyhydroxymethyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0719(R)-N-(2,3-dihydro-1H-indenyl)adenosine
Modified Nucleosides · CAS: 96392-15-3
BX-MN-01891-(2-Deoxy-b-D-xylofuranosyl)-5-methyluracil, 3'-beta-thymidine
Modified Nucleosides · CAS: N/A
Frequently asked questions
Can the package size for S-Adenosylmethionine (SAM) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0069 and CAS 485-80-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.