Linker Phosphoramidites
Spacer-18 Phosphoramidite
Quick view. We supply Spacer-18 Phosphoramidite as a spacer/linker phosphoramidite for inserting defined distance and flexibility into synthetic oligonucleotides. CAS 125607-09-2. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
Spacer-18 Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C42H61N2O10P; molecular weight 784.91).
Spacer-18 Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For Spacer-18 Phosphoramidite, reported solubility: good in most organic solvents. Storage: Storage temp. 2-8°C.
Names and search terms
Confirmed or normalized name variants
- DMT-PEG Phosphoramidite 18
- Hexaethylene glycol phosphoramidite
- Spacer 18(PEG)-DMT CE Phosphoramidite
Useful catalog search terms
- CAS 125607-09-2
- Protected oligonucleotide phosphoramidite building block
- phosphoramidite coupling group
- Linker Phosphoramidites
Physicochemical data
| Key chemistry motifs | phosphoramidite coupling group |
|---|---|
| Boiling point | 763.6±60.0 °C(Predicted) |
| Form | Liquid |
| Color | Colorless to light yellow |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Hexaethylene glycol phosphoramidite (Spacer Phosphoramidite 18) is an amidite reagent for oligonucleotide synthesis. Hexaethylene glycol phosphoramidite can be used as a linker in synthesis of nucleotide chain and qPCR probes.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Related products
2-O-DMTr-Sulfonyldiethanol-CE-Phosphoramidite
Linker Phosphoramidites · CAS: 108783-02-4
BX-LP-00115'-Amino-Modifier C6-TFA CE Phosphoramidite
Linker Phosphoramidites · CAS: 133975-85-6
BX-LP-00126-palmitamidohexyl CE Phosphoramidite
Linker Phosphoramidites · CAS: 1772522-18-5
BX-LP-0013Spacer C12 Phosphoramidite
Linker Phosphoramidites · CAS: 158665-27-1
BX-LP-0014Spacer PEG-N3 Phosphoramidite
Linker Phosphoramidites · CAS: N/A
BX-LP-0016Thiol-Modifier C6 S-S CE Phosphoramidite
Linker Phosphoramidites · CAS: 148254-21-1
Frequently asked questions
Can the package size for Spacer-18 Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-LP-0026 and CAS 125607-09-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Linker Phosphoramidites product family and its named chemistry.