DNA Phosphoramidites
TFA-aminoallyl-dU Phosphoramidite
Quick view. A 2'-deoxyuridine CE phosphoramidite bearing a C5 aminoallyl substituent protected as a trifluoroacetamide, CAS 144253-90-7. CAS 144253-90-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
TFA-aminoallyl-dU Phosphoramidite is classified as dna phosphoramidites (Formula C44H51F3N5O9P; molecular weight 881.87).
TFA-aminoallyl-dU Phosphoramidite — A TFA-protected aminoallyl-dU CE phosphoramidite for research use in preparing amino-functionalized DNA oligonucleotides.
For TFA-aminoallyl-dU Phosphoramidite, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 5-TFA-aa-dU Phosphoramidite
- TFA-aminoallyl-2'-deoxyuridine Phosphoramidite
- 5'-O-DMT-5-TFA-aa-2'-deoxyuridine-3'-CE phosphoramidite
- 5-Aminoallyl-dU CEP
Useful catalog search terms
- 144253-90-7
Physicochemical data
| Nucleoside core | 2'-Deoxyuridine |
|---|---|
| Base modification | C5 E-aminoallyl, N-trifluoroacetyl protected |
| 5' protection | DMTr |
| 3' functionality | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| PubChem CID | 90470044 |
| InChI | InChI=1S/C44H51F3N5O9P/c1-29(2)52(30(3)4)62(59-25-11-23-48)61-37-26-39(51-27-31(40(53)50-42(51)55)12-10-24-49-41(54)44(45,46)47)60-38(37)28-58-43(32-13-8-7-9-14-32,33-15-19-35(56-5)20-16-33)34-17-21-36(57-6)22-18-34/h7-10,12-22,27,29-30,37-39H,11,24-26,28H2,1-6H3,(H,49,54)(H,50,53,55)/b12-10+/t37-,38+,39+,62?/m0/s1 |
| InChIKey | WBARYSWSAVXEHP-CVHHHLGISA-N |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)/C=C/CNC(=O)C(F)(F)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe TFA-aminoallyl-dU Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for TFA-aminoallyl-dU Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DP-0046 and CAS 144253-90-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.