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UNA Phosphoramidites

5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite

Quick view. A fully protected U-UNA building block comprising 2',3'-seco-uridine with 5'-O-DMTr, 2'-O-benzoyl, and 3'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 1120329-48-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Chemical structure of 5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite
Chemical structure
Catalog numberBX-UP-0004
CAS number1120329-48-7
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite is classified as una phosphoramidites (Formula C46H53N4O10P; molecular weight 852.92).

Typical application

5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite — Identity-defined UNA-U phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.

Handling focus

For 5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

InChIKeyMHRGEJFLFYZLJI-LZOZAVILSA-N
NucleobaseUracil
Backbone2',3'-seco-uridine (UNA-U)
Hydroxyl protection5'-O-DMTr and 2'-O-benzoyl
Coupling group2-Cyanoethyl N,N-diisopropylphosphoramidite
InChIInChI=1S/C46H53N4O10P/c1-33(2)50(34(3)4)61(58-29-13-27-47)59-31-41(60-43(49-28-26-42(51)48-45(49)53)32-56-44(52)35-14-9-7-10-15-35)30-57-46(36-16-11-8-12-17-36,37-18-22-39(54-5)23-19-37)38-20-24-40(55-6)25-21-38/h7-12,14-26,28,33-34,41,43H,13,29-32H2,1-6H3,(H,48,51,53)/t41-,43-,61?/m1/s1
SMILESC(C1=CC=CC=C1)(=O)OC[C@H](N1C(NC(C=C1)=O)=O)O[C@H](COC(C1=CC=CC=C1)(C1=CC=C(C=C1)OC)C1=CC=C(C=C1)OC)COP(N(C(C)C)C(C)C)OCCC#N
Canonical SMILESC(C1=CC=CC=C1)(=O)OC[C@H](N1C(NC(C=C1)=O)=O)O[C@H](COC(C1=CC=CC=C1)(C1=CC=C(C=C1)OC)C1=CC=C(C=C1)OC)COP(N(C(C)C)C(C)C)OCCC#N

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Frequently asked questions

Can the package size for 5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-UP-0004 and CAS 1120329-48-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Feature and workflow background

These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.