Anhydro Nucleosides
2,2'-Anhydro-rU
Quick view. We supply 2,2'-Anhydro-rU as an anhydro nucleoside intermediate for nucleoside analog synthesis. CAS 3736-77-4. Catalog target purity: ≥98%.
Product profile
2,2'-Anhydro-rU is classified as nucleoside or protected nucleoside intermediate (Formula C9H10N2O5; molecular weight 226.19).
2,2'-Anhydro-rU can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2,2'-Anhydro-rU, reported solubility: DMSO:2.0(Max Conc. mg/mL);8.84(Max Conc. mM) PBS (pH:7.2):1.0(Max Conc. mg/mL);4.42(Max Conc. mM). Storage: Store at RT.
Names and search terms
Confirmed or normalized name variants
- Anhydro-U
- 2,2'-Anhydro-U
- 02,2-Cycloridine
- 2,2'-Cyclouridine
- O2,2'-CYCLOURIDINE
- 2,2'-ANHYDROURIDINE
- 2,2'-O-Cyclouridine
- β-D-O2,2′-Cyclouridine
Useful catalog search terms
- CAS 3736-77-4
- Nucleoside or protected nucleoside intermediate
- Anhydro Nucleosides
Physicochemical data
| Melting point | 248-251 °C(lit.) |
|---|---|
| Boiling point | 456.3±55.0 °C(Predicted) |
| Density | 2.01±0.1 g/cm3(Predicted) |
| pKa | 12.55±0.40(Predicted) |
| Form | powder to crystal |
| Color | White to Almost white |
| SMILES | C12O[C@@]3([H])[C@H](O)[C@@H](CO)O[C@@]3([H])N1C=CC(=O)N=2 |
| InChI | InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s |
| InChIKey | UUGITDASWNOAGG-CCXZUQQUSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2,2'-Anhydro-rU be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AN-0001 and CAS 3736-77-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Anhydro Nucleosides product family and its named chemistry.