Anhydro Nucleosides
2,3'-Anhydrothymidine
Quick view. We supply 2,3'-Anhydrothymidine as an anhydro nucleoside intermediate for nucleoside analog synthesis. CAS 15981-92-7. Catalog target purity: Specification on request.
Product profile
2,3'-Anhydrothymidine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12N2O3; molecular weight 208.21).
2,3'-Anhydrothymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2,3'-Anhydrothymidine, reported solubility: DMSO (Slightly), Methanol (Slightly, Heated). Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 3-(Hydroxymethyl)-8-methyl-2,3-dihydro-5H,9H-2,5-methanopyrimido[2,1-b][1,5,3]dioxazepin-9-one
- NSC 144601
- Anhydrothymidine
- O2,3'-Cyclothymidine
- 2,3'-O-Cyclothymidine
- 2,3'-Anhydro-D-thymidine
- 2,3'-Anhydro-1-(2'-deoxy--D-threo-pentofuranosyl)thymine
Useful catalog search terms
- CAS 15981-92-7
- Nucleoside or protected nucleoside intermediate
- Anhydro Nucleosides
Physicochemical data
| InChI | 1S/C10H12N2O4/c1-5-3-12-8-2-6(7(4-13)15-8)16-10(12)11-9(5)14/h,6-8,13H,2,4H2,1H3/t6-,7-,8-/m1/s |
|---|---|
| InChIKey | JCSNHEYOIASGKU-BWZBUEFSSA-N |
| SMILES | CC1=C[N@@H]2[C@H]3C[C@@H](OC2=NC1=O)[C@@H](CO)O3 |
| Melting point | 246-247oC |
| Boiling point | 381.8±52.0 °C(Predicted) |
| Density | 1.72±0.1 g/cm3(Predicted) |
| pKa | 13.97±0.10(Predicted) |
| Form | Solid |
| Color | White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2,3'-Anhydrothymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AN-0004 and CAS 15981-92-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Anhydro Nucleosides product family and its named chemistry.