Halogenated Nucleosides
2'-Chloro-2'-deoxy-5-methyluridine
Quick view. We supply 2'-Chloro-2'-deoxy-5-methyluridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 54898-34-9. Catalog target purity: Specification on request.
Product profile
2'-Chloro-2'-deoxy-5-methyluridine is classified as nucleoside or protected nucleoside intermediate (Formula C10H13ClN2O5; molecular weight 276.67).
2'-Chloro-2'-deoxy-5-methyluridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Chloro-2'-deoxy-5-methyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 1-(2-Chloro-2-deoxypentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
- NSC 529514
- 2'-chlorothymidine
- 2'-chlorothymidine
- 2'-Chloro-2'-deoxythymidine
- 2'-Deoxy-2'-chloro-5-methyluridine
- Uridine, 2'-chloro-2'-deoxy-5-methyl-
- 2’-Chloro-2’-deoxy-5-methyluridine, 2’-Chlorothymidine
Useful catalog search terms
- CAS 54898-34-9
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H13ClN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h,5-7,9,14-15H,3H2,1H3,(H,12,16,17) |
|---|---|
| InChIKey | WQMQACLYZYXSDZ-UHFFFAOYSA-N |
| SMILES | Cc1cn(C2OC(CO)C(O)C2Cl)c(=O)nc1O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2’-Chlorothymidine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2'-Chloro-2'-deoxy-5-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0123 and CAS 54898-34-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.