2'-FANA Nucleosides
2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine
Quick view. We supply 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 136675-88-2. Catalog target purity: Specification on request.
Product profile
2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11FN2O4; molecular weight 230.193).
2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 1-(2-Deoxy-2-fluoropentofuranosyl)pyrimidin-2(1H)-one
- 2'-arafluorozebularine
- 1-(2-DEOXY-2-FLUORO-BETA-D-ARABINORIBOFUANOSYL)-2(1H)-PYRIMIDINONE
- 1-[(2R,3S,4R,5R)-3-FLUORO-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]PYRIMIDIN-2-ONE
Useful catalog search terms
- CAS 136675-88-2
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- 2'-FANA Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|---|
| InChI | InChI=1S/C9H11FN2O4/c10-6-7(14)5(4-13)16-8(6)12-3-1-2-11-9(12)15/h1-3,5-8,13-14H,4H2/t5-,6+,7-,8-/m1/s |
| InChIKey | WQIKHPATWLOZFO-ULAWRXDQSA-N |
| SMILES | C1=CN(C(=O)N=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FAN-0020 and CAS 136675-88-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine or the named structural feature represented by this product.