Halogenated Nucleosides
3'-Deoxy-3'-fluoro-5-methyluridine
Quick view. A beta-D 5-methyluridine derivative bearing fluorine at the 3' position of the ribofuranose unit, CAS 125217-37-0. CAS 125217-37-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-Deoxy-3'-fluoro-5-methyluridine is classified as halogenated nucleosides (Formula C10H13FN2O5; molecular weight 260.22).
3'-Deoxy-3'-fluoro-5-methyluridine — Primary literature reports crystallographic analysis of this fluorinated nucleoside's stereochemistry and conformation.
For 3'-Deoxy-3'-fluoro-5-methyluridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 3'-Fluoro-3'-deoxy-5-methyluridine
- 1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)thymine
- 3'-F-5-Me-uridine
- Uridine, 3'-deoxy-3'-fluoro-5-methyl-
Useful catalog search terms
- CAS 125217-37-0
Physicochemical data
| Systematic name | 1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
|---|---|
| Nucleobase | 5-Methyluracil |
| Sugar modification | 3'-fluoro-3'-deoxy |
| PubChem CID | 469286 |
| InChI | InChI=1S/C10H13FN2O5/c1-4-2-13(10(17)12-8(4)16)9-7(15)6(11)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6-,7-,9-/m1/s1 |
| InChIKey | XFLCLDYCKOUGAR-JXOAFFINSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)F)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluoro-5-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-Deoxy-3'-fluoro-5-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0167 and CAS 125217-37-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.