Halogenated Nucleosides
3'-Deoxy-3'-fluoroinosine
Quick view. 3'-Deoxy-3'-fluoroinosine is an inosine nucleoside bearing fluorine at sugar C3', with CAS 117517-20-1. CAS 117517-20-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-Deoxy-3'-fluoroinosine is classified as 3'-fluoro inosine nucleoside (Formula C10H11FN4O4; molecular weight 270.22).
3'-Deoxy-3'-fluoroinosine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 3'-Deoxy-3'-fluoroinosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 3'-Fluoro-3'-deoxyinosine
- TNU0201
- CHEMBL4869277
- RefChem:90359
- PubChem CID 135503550
- Wikidata Q82895967
Useful catalog search terms
- CAS 117517-20-1
Physicochemical data
| IUPAC name | 9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one |
|---|---|
| InChI | InChI=1S/C10H11FN4O4/c11-5-4(1-16)19-10(7(5)17)15-3-14-6-8(15)12-2-13-9(6)18/h2-5,7,10,16-17H,1H2,(H,12,13,18)/t4-,5-,7-,10-/m1/s1 |
| InChIKey | POYFYFKHABGRAR-QYYRPYCUSA-N |
| SMILES | C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O |
| Structural feature | Fluorine replaces the 3'-hydroxyl group |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluoroinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-HN-00042'-Chloro-2'-deoxycytidine
Halogenated Nucleosides · CAS: 10212-19-8
BX-HN-00055-Bromo-2'-deoxycytidine
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BX-HN-01535-Fluoro-2'-deoxycytidine
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Frequently asked questions
Can the package size for 3'-Deoxy-3'-fluoroinosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0158 and CAS 117517-20-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.