Halogenated Nucleosides
5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine
Quick view. We supply 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 162204-30-0. Catalog target purity: Specification on request.
Product profile
5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is classified as nucleoside or protected nucleoside intermediate (Formula C15H22FN3O6; molecular weight 359.35).
5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine, reported solubility: Methanol (Slightly). Storage: Sealed in dry,2-8°C.
Names and search terms
Confirmed or normalized name variants
- 5'-deoxy-5-fluoro-N4-(3-methyl-1-butyloxycarbonyl)cytidine
- CS-935
- Capecitabine-3
- Capecitabin iMpurity E
- Capecitabine iMpurity F
- Capecitabine EP Impurity E
- Capecitabine Impurity E(EP)
- Capecitabine 3-Methylbutyloxy Imp
Useful catalog search terms
- CAS 162204-30-0
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C15H22FN3O6/c1-7(2)4-5-24-15(23)18-12-9(16)6-19(14(22)17-12)13-11(21)10(20)8(3)25-13/h6-8,10-11,13,20-21H,4-5H2,1-3H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s |
|---|---|
| InChIKey | PPVCPOIDSSQXMR-UORFTKCHSA-N |
| SMILES | C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=NC2=O)NC(=O)OCCC(C)C)F)O)O |
| Melting point | 106-109°C |
| Density | 1.49±0.1 g/cm3(Predicted) |
| pKa | 5.44±0.40(Predicted) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0176 and CAS 162204-30-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.