DMTr-protected Nucleosides
5'-O-DMTr-5-Me-dC(Bz)
Quick view. We supply 5'-O-DMTr-5-Me-dC(Bz) as a DMTr-protected nucleoside intermediate for selective oligonucleotide building-block synthesis. CAS 104579-03-5. Catalog target purity: ≥98%.
Product profile
5'-O-DMTr-5-Me-dC(Bz) is classified as nucleoside or protected nucleoside intermediate (Formula C38H37N3O7; molecular weight 647.72).
5'-O-DMTr-5-Me-dC(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-DMTr-5-Me-dC(Bz), reported solubility: DMSO: 41.67 mg/mL (64.33 mM; Need ultrasonic). Storage: Store at 0°C.
Names and search terms
Confirmed or normalized name variants
- -O-(4,4&rsquo
- DMT-NBZ-5-METHYL DC
- 5'-O-DMT-N4-Bz-5-Me-dC
- 5'-O-DMT-N4-Benzoyl-2'-Deoxy-5-Methylcytidine
- -Dimethoxytrityl)-n4-benzoyl-5-methyl-2&rsquo
- 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methylcytidine
- Cytidine, N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-deoxy-5-Methyl-
Useful catalog search terms
- CAS 104579-03-5
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- DMTr-protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection |
|---|---|
| Density | 1.26±0.1 g/cm3(Predicted) |
| pKa | 8.69±0.40(Predicted) |
| Form | Solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
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DMTr-protected Nucleosides · CAS: N/A
BX-PN-00193'-O-DMTr-2'-O-Me-rU
DMTr-protected Nucleosides · CAS: N/A
BX-PN-00203'-O-DMTr-dA(Bz)
DMTr-protected Nucleosides · CAS: 140712-79-4
BX-PN-00265'-O-DMTr-2'-F-dC(Bz)
DMTr-protected Nucleosides · CAS: N/A
BX-PN-00275'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU
DMTr-protected Nucleosides · CAS: 242147-79-1
BX-PN-00285'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rA(Ac)
DMTr-protected Nucleosides · CAS: 863408-41-7
Frequently asked questions
Can the package size for 5'-O-DMTr-5-Me-dC(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0054 and CAS 104579-03-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry.