DMTr-protected Nucleosides
5'-O-DMTr-N1-Me-pseudoU
Quick view. We supply 5'-O-DMTr-N1-Me-pseudoU as a DMTr-protected pseudouridine-family nucleoside for modified RNA monomer synthesis. CAS 875302-39-9. Catalog target purity: ≥95%.
Product profile
5'-O-DMTr-N1-Me-pseudoU is classified as nucleoside or protected nucleoside intermediate.
5'-O-DMTr-N1-Me-pseudoU can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-DMTr-N1-Me-pseudoU, modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
Names and search terms
Confirmed or normalized name variants
- 5'-DMT-N1-Me-Pseudouricdine
- 5'-O-DMT-N1-methylpseudouridine
- 5'-O-(4,4'-Dimethoxytrityl)-N1-methylpseudouridine
- 5'-O-(4,4'-dimethoxitrityl)-1-N-methylpseudouridine
- 5'-O-DMT-N1-Me-pseudoU
Useful catalog search terms
- CAS 875302-39-9
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- DMTr-protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
These points describe 5'-O-DMTr-N1-Me-pseudoU or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-O-DMTr-N1-Me-pseudoU be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0056 and CAS 875302-39-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5'-O-DMTr-N1-Me-pseudoU or the named structural feature represented by this product.