Halogenated Nucleosides
5'-O-(tert-Butyldimethylsilyl)-5-iodo-2'-deoxyuridine
Quick view. A protected halogenated nucleoside comprising 5-iodo-2'-deoxyuridine with a 5'-O-tert-butyldimethylsilyl group, CAS 134218-81-8. CAS 134218-81-8. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-O-(tert-Butyldimethylsilyl)-5-iodo-2'-deoxyuridine is classified as halogenated nucleosides (Formula C15H25IN2O5Si; molecular weight 468.36).
5'-O-(tert-Butyldimethylsilyl)-5-iodo-2'-deoxyuridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 5'-O-(tert-Butyldimethylsilyl)-5-iodo-2'-deoxyuridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-TBDMS-5-iodo-2'-deoxyuridine
- 2'-Deoxy-5'-O-TBDMS-5-Iodo-Uridine
- TBDMS-I-dU
Useful catalog search terms
- CAS 134218-81-8
- Wikidata Q82248817
- ChemicalBook CB02449511
Physicochemical data
| InChI | InChI=1S/C15H25IN2O5Si/c1-15(2,3)24(4,5)22-8-11-10(19)6-12(23-11)18-7-9(16)13(20)17-14(18)21/h7,10-12,19H,6,8H2,1-5H3,(H,17,20,21)/t10-,11+,12+/m0/s1 |
|---|---|
| InChIKey | OOAVDWDELLQGHO-QJPTWQEYSA-N |
| SMILES | CC(C)(C)[Si](C)(C)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)I)O |
| Halogen position | Iodine at uracil C5 |
| Sugar modification | 2'-Deoxy |
| Hydroxyl protection | 5'-O-tert-butyldimethylsilyl ether |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 5'-O-(tert-Butyldimethylsilyl)-5-iodo-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0027 and CAS 134218-81-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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