ddNTPs
5-Propargylamino-ddCTP trisodium salt
Quick view. A trisodium 5-propargylamino-ddCTP chain terminator for sequencing-reagent and post-incorporation labeling research. Parent CAS 114748-56-0; this identifier does not represent the complete catalog product form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Structure
Structure form boundary. The displayed drawing omits catalog counterions and does not establish the complete supplied form, counterion stoichiometry or hydration state.
Identity of the displayed counterion-free structure
Scope. These values describe only the counterion-free structure shown above. They do not identify the complete catalog salt or establish counterion stoichiometry.
| Depicted identity | 5-Propargylamino-ddCTP |
|---|---|
| Depicted form | Counterion-free structure |
| Source database | PubChem |
| PubChem CID | 21779042 |
| Molecular formula | C12H19N4O12P3 |
| Molecular weight | 504.22 g/mol |
| InChIKey | UZTVDBNPCNJIGN-VHSXEESVSA-N |
Machine-readable identifiers for the displayed structure
| SMILES | C1C[C@@H](O[C@@H]1COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N2C=C(C(=NC2=O)N)C#CCN |
|---|---|
| InChI | InChI=1S/C12H19N4O12P3/c13-5-1-2-8-6-16(12(17)15-11(8)14)10-4-3-9(26-10)7-25-30(21,22)28-31(23,24)27-29(18,19)20/h6,9-10H,3-5,7,13H2,(H,21,22)(H,23,24)(H2,14,15,17)(H2,18,19,20)/t9-,10+/m0/s1 |
Form boundary. The reviewed PubChem record establishes the counterion-free parent stereochemistry, not the complete catalog trisodium salt or counterion stoichiometry.
Identifier context
These notes preserve the current catalog identifiers while making their review boundary explicit.
Parent CAS 114748-56-0 identifies the counterion-free parent and is shared by multiple BX Lab catalog records; it does not establish the complete trisodium product form. The trisodium formula and molecular weight remain under exact-form source review. Published purity and package size use catalog fallback values; physical form, concentration, storage and stability are omitted pending source-compliant evidence. Confirm the exact salt, counterion, concentration and supplied form when requesting a quote.
Product profile
5-Propargylamino-ddCTP trisodium salt is classified as ddntps.
5-Propargylamino-ddCTP trisodium salt — Chain-termination and sequencing-reagent research
For 5-Propargylamino-ddCTP trisodium salt, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- 5-PA-ddCTP trisodium
- 5-Propargylamino-2',3'-dideoxycytidine 5'-triphosphate trisodium salt
Useful catalog search terms
- 5-PA-ddCTP
Physicochemical data
| Parent CAS | 114748-56-0 |
|---|---|
| CAS basis | Parent identity only; not the complete catalog trisodium-salt form |
| CAS publication scope | parent-only |
| Parent molecular formula | C12H19N4O12P3 |
| Parent molecular weight | 504.22 |
| Trisodium identity status | Complete trisodium formula and molecular weight pending exact-form source verification |
| Modification | C5 propargylamino handle on 2',3'-dideoxycytidine triphosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Post-incorporation labeling and cyanine-dye nucleotide-conjugate research
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 5-Propargylamino-ddCTP trisodium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-Amino-3'-deoxy-dATP Sodium Salt
ddNTPs · Parent/free-acid CAS: 90053-18-2
BX-DDNT-00023'-Amino-3'-deoxy-dCTP Sodium Salt
ddNTPs · CAS: 90053-17-1
BX-DDNT-00033'-Amino-3'-deoxy-dGTP Sodium Salt
ddNTPs · CAS: 90053-19-3
BX-DDNT-00043'-Amino-3'-deoxy-dTTP Sodium Salt
ddNTPs · Parent/free-acid CAS: 90053-16-0
BX-DDNT-00053'-Azido-2',3'-dideoxy-dATP Sodium Salt
ddNTPs · CAS: 92562-94-2
BX-DDNT-00063'-Azido-2',3'-dideoxy-dCTP Sodium Salt
ddNTPs · CAS: 92562-77-1
Frequently asked questions
Can the package size for 5-Propargylamino-ddCTP trisodium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0010 and Parent CAS 114748-56-0 (not a complete catalog-product CAS), the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.