RNA (2'-O-TBDMS) Phosphoramidites
6'-O-DMTr-2'-O-TBDMS-5'-Homo-A(Bz)-3'-CE-Phosphoramidite
Quick view. We supply 6'-O-DMTr-2'-O-TBDMS-5'-Homo-A(Bz)-3'-CE-Phosphoramidite as a homo-adenosine TBDMS-protected RNA amidite for noncanonical backbone and spacing studies. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%.
Product profile
6'-O-DMTr-2'-O-TBDMS-5'-Homo-A(Bz)-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
6'-O-DMTr-2'-O-TBDMS-5'-Homo-A(Bz)-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For 6'-O-DMTr-2'-O-TBDMS-5'-Homo-A(Bz)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 6'-O-DMT-2'-O-TBDMS-5'-Homo-A(Bz)-3'-CE-Phosphoramidite
- 6'-O-DMTr-2'-O-TBDMS-5'-Homo-A(Bz)-3'-2-cyanoethyl phosphoramidite
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- TBDMS protection
- phosphoramidite coupling group
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; TBDMS protection; phosphoramidite coupling group |
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Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
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Frequently asked questions
Can the package size for 6'-O-DMTr-2'-O-TBDMS-5'-Homo-A(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-R2OT-0001, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry.