RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite
Quick view. We supply DMTr-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite as a 5-fluorouridine RNA amidite for incorporating fluorinated uracil into RNA. CAS 173241-78-6. Catalog target purity: ≥98%.
Product profile
DMTr-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C45H60FN4O9PSi; molecular weight 879.05).
DMTr-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-DMTr-2'-O-TBS-C5-F-3'-O-CEP-URIDINE
- DMT-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite
- DMTr-2'-O-TBDMS-5-F-rU-3'-2-cyanoethyl phosphoramidite
Useful catalog search terms
- CAS 173241-78-6
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- TBDMS protection
- phosphoramidite coupling group
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; TBDMS protection; phosphoramidite coupling group |
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Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
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Frequently asked questions
Can the package size for DMTr-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-R2OT-0004 and CAS 173241-78-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry.