Halogenated Nucleosides
8-Bromo-2'-deoxyguanosine
Quick view. We supply 8-Bromo-2'-deoxyguanosine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 13389-03-2. Catalog target purity: Specification on request.
Product profile
8-Bromo-2'-deoxyguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12BrN5O4; molecular weight 346.14).
8-Bromo-2'-deoxyguanosine is useful as the starting structure for 2'-deoxyguanosine nucleotides, which are modified in position 8.
For 8-Bromo-2'-deoxyguanosine, reported solubility: DMSO, Warm Water. Storage: -20°C Freezer.
Names and search terms
Confirmed or normalized name variants
- 8-Br-dG
- NSC 105830
- 8-Br-2'-dG
- 2'-Deoxy-8-bromoguanosine
- 8-Bromo-2'-deoxy-D-guanosine
- -4-hydroxy-5-(hydroxymethyl)
- 2-Amino-8-bromo-9-((2R,4S,5R)
Useful catalog search terms
- CAS 13389-03-2
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H12BrN5O4/c11-9-13-6-7(14-10(12)15-8(6)19)16(9)5-1-3(18)4(2-17)20-5/h3-5,17-18H,1-2H2,(H3,12,14,15,19)/t3-,4+,5+/m0/s |
|---|---|
| InChIKey | MKDXZFVCXWXGBQ-VPENINKCSA-N |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C3=C(C(=O)N=C(N3)N)N=C2Br)CO)O |
| Melting point | >250°C dec. |
| Density | 2.45 |
| pKa | 8.76±0.20(Predicted) |
| Form | Powder |
| Color | White to Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 8-Bromo-2'-deoxyguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Bromo-2'-deoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0024 and CAS 13389-03-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.