2'-F Nucleosides
2',5'-Dideoxy-2'-fluoro-5'-iodouridine
Quick view. Uridine derivative bearing a 2'-fluoro substituent and a 5'-iodomethyl group on a 2',5'-dideoxy sugar. CAS 211694-25-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',5'-Dideoxy-2'-fluoro-5'-iodouridine is classified as 2'-f nucleosides (Formula C9H10FIN2O4; molecular weight 356.09 g/mol).
2',5'-Dideoxy-2'-fluoro-5'-iodouridine can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For 2',5'-Dideoxy-2'-fluoro-5'-iodouridine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- Uridine, 2',5'-dideoxy-2'-fluoro-5'-iodo-
Useful catalog search terms
- 211694-25-6
Physicochemical data
| Base scaffold | Uridine |
|---|---|
| Sugar modification | 2',5'-dideoxy |
| 2'-substitution | Fluoro |
| 5'-substitution | Iodomethyl |
| InChIKey | QLNYKCHAXHDXHT-XVFCMESISA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2',5'-Dideoxy-2'-fluoro-5'-iodouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2'-Deoxy-2'-fluoroinosine
2'-F Nucleosides · CAS: 80049-87-2
BX-MN-01802'-Fluoro-2'-deoxyadenosine
2'-F Nucleosides · CAS: 64183-27-3
BX-MN-01812'-Fluoro-2'-deoxyuridine
2'-F Nucleosides · CAS: 784-71-4
BX-MN-01822'-Deoxy-2'-fluorocytidine
2'-F Nucleosides · CAS: 10212-20-1
BX-MN-01832'-Deoxy-2'-fluoroguanosine
2'-F Nucleosides · CAS: 78842-13-4
BX-2FN-00034'-Azido-2'-deoxy-2'-fluoroaracytidine
2'-F Nucleosides · CAS: 1011529-10-4
Frequently asked questions
Can the package size for 2',5'-Dideoxy-2'-fluoro-5'-iodouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FN-0109 and CAS 211694-25-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.