Amino-modified Nucleosides
2'-amino-2'-deoxyguanosine
Quick view. We supply 2'-amino-2'-deoxyguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 60966-26-9. Catalog target purity: Specification on request.
Product profile
2'-amino-2'-deoxyguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N6O4; molecular weight 282.26).
2'-amino-2'-deoxyguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-amino-2'-deoxyguanosine, reported solubility: DMSO (Slightly, Heated), Water (Slightly, Heated). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 2'-NH2-dG
- -AMino-2´
- 2'-NH2-2-NH2-dA
- 2''-AMINO-D-GUANOSINE
- 2'-Deoxy-2'-aminoguanosine
- 2′-Amino-2′-Deoxyfuanosine
- 2'-Amino-2'-deoxy-D-guanosine
- Guanosine, 2'-amino-2'-deoxy-
Useful catalog search terms
- CAS 60966-26-9
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C10H14N6O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1,11H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s |
| InChIKey | ROPTVRLUGSPXNH-DXTOWSMRSA-N |
| SMILES | N=c1nc(O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3N)c2[nH]1 |
| Melting point | 252-254 °C |
| Density | 2.25±0.1 g/cm3(Predicted) |
| Form | Powder |
| Color | White to Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-amino-2'-deoxyguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-amino-2'-deoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0104 and CAS 60966-26-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.