Amino-modified Nucleosides
2-Amino-3'-deoxy-3'-fluoroadenosine
Quick view. We supply 2-Amino-3'-deoxy-3'-fluoroadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 125391-75-5. Catalog target purity: Specification on request.
Product profile
2-Amino-3'-deoxy-3'-fluoroadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H13FN6O3; molecular weight 284.25).
2-Amino-3'-deoxy-3'-fluoroadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-Amino-3'-deoxy-3'-fluoroadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- Adenosine, 2-amino-3'-deoxy-3'-fluoro-
- Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI)
Useful catalog search terms
- CAS 125391-75-5
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C10H13FN6O3/c11-4-3(1-18)20-9(6(4)19)17-2-14-5-7(12)15-10(13)16-8(5)17/h2-4,6,9,18-19H,1H2,(H4,12,13,15,16)/t3-,4-,6-,9-/m1/s |
| InChIKey | BBWXIJICDDYYJZ-DXTOWSMRSA-N |
| SMILES | C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)N)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2-Amino-3'-deoxy-3'-fluoroadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-Amino-3'-deoxy-3'-fluoroadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0140 and CAS 125391-75-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.