2'-FANA Nucleosides
2'-FANA-dC
Quick view. We supply 2'-FANA-dC as a 2'-fluoro-arabino cytidine nucleoside for FANA oligo building blocks. CAS 56632-83-8. Catalog target purity: Specification on request.
Product profile
2'-FANA-dC is classified as nucleoside or protected nucleoside intermediate (Formula C9H12FN3O4; molecular weight 245.21).
2'-FANA-dC can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-FANA-dC, reported solubility: DMSO: Soluble Methanol: Soluble. Storage: Keep in dark place,Inert atmosphere,Room temperature.
Names and search terms
Confirmed or normalized name variants
- 2’-Deoxy-2’-fluoro-β-D-arabinocytidine
- 2'-Deoxy-2'-fluoro-beta-D-arabinocytidine
- 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine
- 2’-Deoxy-2’-fluoro-beta-D-arabinocytidine, FAC
- 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)cytosine
- FN-008 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine
- 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine
- 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)cytosine HCl
Useful catalog search terms
- CAS 56632-83-8
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- 2'-FANA Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|---|
| Melting point | 136-138 °C |
| Boiling point | 500.1±60.0 °C(Predicted) |
| Density | 1.82±0.1 g/cm3(Predicted) |
| pKa | 12.84±0.70(Predicted) |
| Form | Solid |
| Color | White to off-white |
| InChI | InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6+,7-,8-/m1/s |
| InChIKey | NVZFZMCNALTPBY-PXBUCIJWSA-N |
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-FANA-dC or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-FANA-dC be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0162 and CAS 56632-83-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-FANA-dC or the named structural feature represented by this product.