2'-FANA Nucleosides
2'-FANA-dT
Quick view. We supply 2'-FANA-dT as a 2'-fluoro-arabino thymidine nucleoside for FANA-modified oligonucleotide chemistry. CAS 69256-17-3. Catalog target purity: Specification on request.
Product profile
2'-FANA-dT is classified as nucleoside or protected nucleoside intermediate (Formula C10H13FN2O5; molecular weight 260.22).
2'-FANA-dT can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-FANA-dT, storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- FMAU
- D-FMAU
- Ara-2'-F-2'-dT
- 2'-Fluoro-5-methylarabinosyluracil
- FMAU, 2'-Fluoro-5-methylarabinosyluracil
- 2’-Deoxy-2’-fluoro-5-methyl-β-D-arabinouridine
- 2'-Fluoro-5-methyl-1--D-arabinofuranosyluracil
- 1-(2-Fluoro-2-deoxy-β-D-arabinofuranosyl)thymine
Useful catalog search terms
- CAS 69256-17-3
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- 2'-FANA Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|---|
| Density | 1.55±0.1 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
| InChI | InChI=1S/C10H13FN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6+,7-,9-/m1/s |
| InChIKey | GBBJCSTXCAQSSJ-JVZYCSMKSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-FANA-dT or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-FANA-dT be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0163 and CAS 69256-17-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-FANA-dT or the named structural feature represented by this product.