2'-FANA Nucleosides
2'-FANA-dU
Quick view. We supply 2'-FANA-dU as a 2'-fluoro-arabino uridine nucleoside for FANA oligo chemistry. CAS 69123-94-0. Catalog target purity: Specification on request.
Product profile
2'-FANA-dU is classified as nucleoside or protected nucleoside intermediate (Formula C9H11FN2O5; molecular weight 246.19).
2'-FANA-dU can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-FANA-dU, reported solubility: Methanol: Soluble. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- FAU
- 2'-Deoxy-2'-fluoro-beta-D-arabinouridine
- 2'-Fluoro-2'-deoxy-arabinofuranosyl-uridine
- 2'-Fluoro-arabinofuranosyl-2'-deoxy-uridine
- 1,3-Dimethyl-4-Amino-5-Formamide-Uracil FAU
- 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil
- 2’-fluoro-5-ethyl-1-beta-d-arabinofuranosyluracil
- 2'-FLUORO 2'-DEOXYURACIL-BETA-D-ARABINOFURANOSIDE
Useful catalog search terms
- CAS 69123-94-0
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- 2'-FANA Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|---|
| Melting point | 162 °C(Solv: chloroform (67-66-3); methanol (67-56-1)) |
| Density | 1.63±0.1 g/cm3(Predicted) |
| pKa | 9.39±0.10(Predicted) |
| Form | Solid |
| Color | White to off-white |
| SMILES | [C@@H]1([C@@H](F)[C@H](O)[C@@H](CO)O1)N1C=CC(=O)NC1=O |&1:0,1,3,5,r| |
| InChI | InChI=1/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6+,7-,8-/s |
| InChIKey | UIYWFOZZIZEEKJ-QOUWCGOQNA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-FANA-dU or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-FANA-dU be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0172 and CAS 69123-94-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-FANA-dU or the named structural feature represented by this product.