Amino-modified Nucleosides
3'-Amino-3'-deoxy-N6,N6-dimethyladenosine
Quick view. We supply 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 58-60-6. Catalog target purity: Specification on request.
Product profile
3'-Amino-3'-deoxy-N6,N6-dimethyladenosine is classified as nucleoside or protected nucleoside intermediate (Formula C12H18N6O3; molecular weight 294.31).
3'-Amino-3'-deoxy-N6,N6-dimethyladenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine, reported solubility: H₂O: 50 mg/mL, clear, slightly yellow. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- puromycin aminonucleoside
- Nsc3056
- Aids000507
- aminonucleoside
- 3′-Amino-3′-deoxy-N6
- aminonucleosidepuromycin
- PuroMycin aMinonucleosid
- stylomycinaminonucleoside
Useful catalog search terms
- CAS 58-60-6
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | 1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7+,9+,12-/m1/s |
| InChIKey | RYSMHWILUNYBFW-GRIPGOBMSA-N |
| SMILES | CN(C)c1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H](N)[C@@H]3O |
| Melting point | 235℃ (Decomposition) |
| Boiling point | 436.08°C (rough estimate) |
| Density | 1.2131 (rough estimate) |
| pKa | 13.26±0.70(Predicted) |
| Form | liquid |
| Color | White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0098 and CAS 58-60-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.