Amino-modified Nucleosides
5'-Amino-5'-deoxyguanosine
Quick view. We supply 5'-Amino-5'-deoxyguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5'-Amino-5'-deoxyguanosine is classified as nucleoside or protected nucleoside intermediate.
5'-Amino-5'-deoxyguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-Amino-5'-deoxyguanosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-Amino-5'-deoxyguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-Amino-5'-deoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0093, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5'-Amino-5'-deoxyguanosine or the named structural feature represented by this product.
- Synthesis of 5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate and its enzymatic incorporation at the 5'-termini of RNA molecules. (2007)
- Preparation and purification of 5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate and its initiation properties with T7 RNA polymerase. (2008)
- Chemical syntheses of inhibitory substrates of the RNA-RNA ligation reaction catalyzed by the hairpin ribozyme. (2004)
- Specificity of cGMP binding to a purified cGMP-stimulated phosphodiesterase from bovine adrenal tissue. (1985)