Amino-modified Nucleosides
5'-Amino-5'-deoxythymidine
Quick view. We supply 5'-Amino-5'-deoxythymidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 25152-20-9. Catalog target purity: Specification on request.
Product profile
5'-Amino-5'-deoxythymidine is classified as nucleoside or protected nucleoside intermediate (Formula C10H15N3O4; molecular weight 241.24).
5'-Amino-5'-deoxythymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-Amino-5'-deoxythymidine, reported solubility: DMSO (Slightly), Methanol (Slightly). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 5'-Amino-5'-deoxy-D-thymidine
- Thymidine, 5'-amino-5'-deoxy-
Useful catalog search terms
- CAS 25152-20-9
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C10H15N3O4/c1-5-4-13(10(16)12-9(5)15)8-2-6(14)7(3-11)17-8/h4,6-8,14H,2-3,11H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s |
| InChIKey | PYWLBQPICCQJFF-XLPZGREQSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CN)O |
| Melting point | 171 - 173°C |
| Density | 1.394±0.06 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
| Form | Solid |
| Color | Off-White to Pale Yellow |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-Amino-5'-deoxythymidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-Amino-5'-deoxythymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0063 and CAS 25152-20-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.