Amino-modified Nucleosides
5-Aminouridine
Quick view. We supply 5-Aminouridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 2149-76-0. Catalog target purity: Specification on request.
Product profile
5-Aminouridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H13N3O6; molecular weight 259.22).
5-Aminouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-Aminouridine, storage: −20°C. Form: Solid.
Names and search terms
Confirmed or normalized name variants
- Uridine, 5-amino-
- 5-Aminouridine Hcl
- 5-AminouridineHClsalt
- Uridine, 5-amino-(6CI,7CI,8CI,9CI)
- 5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- 5-azanyl-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- 5-amino-1-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrimidine-2,4-quinone
Useful catalog search terms
- CAS 2149-76-0
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| Melting point | 214-216 °C |
| Density | 1.712±0.06 g/cm3(Predicted) |
| pKa | 9.31±0.10(Predicted) |
| Form | Solid |
| Color | Off-white to light yellow |
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N |
| InChI | InChI=1S/C9H13N3O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h,4-6,8,13-15H,2,10H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s |
| InChIKey | YBTWWWIJBCCYNR-UAKXSSHOSA-N |
| Identity note | CAS and structure correspond to the ribonucleoside identity; confirm hydration and salt form on the current specification. |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5-Aminouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-Aminouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0090 and CAS 2149-76-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.