Protected Nucleosides
5'-O-TBDMS-3'-O-TBDMS-5-I-dC
Quick view. We supply 5'-O-TBDMS-3'-O-TBDMS-5-I-dC as a silyl-protected ribonucleoside intermediate for RNA monomer and specialty nucleoside synthesis. CAS 478843-96-8. Catalog target purity: Specification on request.

Product profile
5'-O-TBDMS-3'-O-TBDMS-5-I-dC is classified as nucleoside or protected nucleoside intermediate (Formula C21H40IN3O4Si; molecular weight 581.64 g/mol (calculated from molecular formula)).
5'-O-TBDMS-3'-O-TBDMS-5-I-dC can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-TBDMS-3'-O-TBDMS-5-I-dC, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Cytidine, 2′-deoxy-3′,5′-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-5-iodo-
Useful catalog search terms
- CAS 478843-96-8
- Nucleoside or protected nucleoside intermediate
- TBDMS protection
- Protected Nucleosides
Physicochemical data
| Key chemistry motifs | TBDMS protection |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-TBDMS-3'-O-TBDMS-5-I-dC be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0058 and CAS 478843-96-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.
