Amino-modified Nucleosides
N4-aminocytidine
Quick view. We supply N4-aminocytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 57294-74-3. Catalog target purity: Specification on request.
Product profile
N4-aminocytidine is classified as nucleoside or protected nucleoside intermediate (Formula C9H14N4O5; molecular weight 258.23).
N4-aminocytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N4-aminocytidine, reported solubility: DMSO (Slightly), Water (Slightly). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 4-Hydrazinyl-1-pentofuranosylpyrimidin-2(1H)-one
- N4-NH2-Cr
- Ccris 2527
- N-Aminocytidine
- uridine,4-hydrazone
- n(sup4)-aminocytidine
- N4-AMINOCYTIDINE USP/EP/BP
- N
Useful catalog search terms
- CAS 57294-74-3
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C9H14N4O5/c10-12-5-1-2-13(9(17)11-5)8-7(16)6(15)4(3-14)18-8/h1-2,4,6-8,14-16H,3,10H2,(H,11,12,17)/t4-,6-,7-,8?/m1/s |
| InChIKey | RSSRMDMJEZIUJX-ZRTZXPPTSA-N |
| SMILES | NNc1ccn(C2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n |
| Melting point | >160°C (sublime) |
| Boiling point | 401.48°C (rough estimate) |
| Density | 1.3656 (rough estimate) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe N4-aminocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N4-aminocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0096 and CAS 57294-74-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.