Amino-modified Nucleosides
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
Quick view. We supply 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 174221-86-4. Catalog target purity: Specification on request.
Product profile
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine is classified as nucleoside or protected nucleoside intermediate (Formula C30H31N3O7; molecular weight 545.59 g/mol (calculated from molecular formula)).
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- STK368466
Useful catalog search terms
- CAS 174221-86-4
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C30H31N3O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-27(35)26(31)28(40-24)33-17-16-25(34)32-29(33)36/h3-17,24,26-28,35H,18,31H2,1-2H3,(H,32,34,36)/t24-,26-,27-,28-/m1/s |
| InChIKey | JKAMWKLYJHJIFE-YULOIDQLSA-N |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CC(=O)NC5=O)N)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0037 and CAS 174221-86-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.