Amino-modified Nucleosides
2'-amino-2'-deoxyuridine
Quick view. We supply 2'-amino-2'-deoxyuridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 26889-39-4. Catalog target purity: Specification on request.
Product profile
2'-amino-2'-deoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H13N3O5; molecular weight 243.22).
2'-amino-2'-deoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-amino-2'-deoxyuridine, reported solubility: DMSO (Slightly), Methanol (Slightly, Sonicated). Storage: under inert gas (nitrogen or Argon) at 2–8 °C.
Names and search terms
Confirmed or normalized name variants
- 2'-Amino-D-uridine
- 2'-NH2-dU
- 2'-Amino-2'-deoxy-D-uridine
- Uridine, 2'-amino-2'-deoxy-
- 2'-Amino-D-uridine USP/EP/BP
- 1-(2-amino-2-deoxy-β-D-ribofuranosyl)uracil
- 2''-AMINO-2''-DEOXYURIDINE (2''-DEOXY-2''-AMINOURIDINE)
- 1-[3-AMINO-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-3H-PYRIMIDINE-2,4-DIONE
Useful catalog search terms
- CAS 26889-39-4
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C9H13N3O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3,10H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s |
| InChIKey | LLIPTMWIZVIUSX-XVFCMESISA-N |
| SMILES | C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)N |
| Melting point | 196-198 °C(Solv: ethanol (64-17-5)) |
| Density | 1.555±0.06 g/cm3(Predicted) |
| pKa | 9.39±0.10(Predicted) |
| Form | Powder |
| Color | Off-white to Yellow |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-amino-2'-deoxyuridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-amino-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0065 and CAS 26889-39-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.