Modified Nucleotides
2'-OMe-CTP Sodium Salt
Quick view. We supply 2'-OMe-CTP Sodium Salt as a 2'-O-methyl nucleotide used to prepare or evaluate modified RNA with improved nuclease resistance and altered immune recognition. CAS 143028-98-2. Catalog target purity: ≥98%.
Product profile
2'-OMe-CTP Sodium Salt is classified as nucleotide or nucleotide analog (Formula C10H18N3O14P3; molecular weight 497.18).
2'-OMe-CTP Sodium Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2'-OMe-CTP Sodium Salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Methyl-Cytidine-5'-triphosphate
- 5'-(tetrahydrogen triphosphate), 2'-O-methyl-Cytidine
- Cytidine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-
Useful catalog search terms
- CAS 143028-98-2
- Nucleotide or nucleotide analog
- 2'-O-methyl modification
- triphosphate group
- Modified Nucleotides
Physicochemical data
| Key chemistry motifs | 2'-O-methyl modification; triphosphate group |
|---|---|
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
| Boiling point | 811.2±75.0 °C(Predicted) |
| Density | 2.28±0.1 g/cm3(Predicted) |
| pKa | 0.80±0.50(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-OMe-CTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-OMe-CTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0035 and CAS 143028-98-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry.