Modified Nucleotides
2'-OMe-UTP Sodium Salt
Quick view. We supply 2'-OMe-UTP Sodium Salt as a 2'-O-methyl nucleotide used to prepare or evaluate modified RNA with improved nuclease resistance and altered immune recognition. CAS 143028-99-3. Catalog target purity: Specification on request.
Product profile
2'-OMe-UTP Sodium Salt is classified as nucleotide or nucleotide analog (Formula C10H17N2O15P3; molecular weight 498.168).
2'-OMe-UTP Sodium Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2'-OMe-UTP Sodium Salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Methyluridine-5'-triphosphate
- 5'-(tetrahydrogen triphosphate), 2'-O-methyl-Uridine
Useful catalog search terms
- CAS 143028-99-3
- Nucleotide or nucleotide analog
- 2'-O-methyl modification
- triphosphate group
- Modified Nucleotides
Physicochemical data
| Key chemistry motifs | 2'-O-methyl modification; triphosphate group |
|---|---|
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-OMe-UTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-OMe-GDP Disodium Salt
Modified Nucleotides · CAS: 78771-34-3
BX-INTE-00143'-OMe-GMP
Modified Nucleotides · CAS: 400806-41-9
BX-INTE-00153'-OMe-GMP TEA Salt
Modified Nucleotides · CAS: 860605-85-2
BX-INTE-0021Im-3'-OMe-GMP
Modified Nucleotides · CAS: 1005791-93-4
BX-INTE-0023Im-GDP
Modified Nucleotides · CAS: 1199264-75-9
BX-MN-0025(-)-Emtricitabine Triphosphate Tetrasodium Salt
Modified Nucleotides · CAS: 1188407-46-6
Frequently asked questions
Can the package size for 2'-OMe-UTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0036 and CAS 143028-99-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry.