Amino-modified Nucleosides
5'-Amino-5'-deoxyadenosine
Quick view. An adenosine derivative in which the 5'-hydroxyl is replaced by a primary amino group, CAS 14365-44-7. CAS 14365-44-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-Amino-5'-deoxyadenosine is classified as amino-modified nucleosides (Formula C10H14N6O3; molecular weight 266.26).
5'-Amino-5'-deoxyadenosine — A 5'-amino-functionalized adenosine derivative for research use in modified purine nucleoside synthesis.
For 5'-Amino-5'-deoxyadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 5'-Aminoadenosine
- 5'-Deoxy-5'-aminoadenosine
- Adenosine, 5'-amino-5'-deoxy-
- 5'-NH-Ado
Useful catalog search terms
- 14365-44-7
Physicochemical data
| Systematic name | (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(aminomethyl)tetrahydrofuran-3,4-diol |
|---|---|
| Nucleoside core | Adenosine |
| Sugar modification | 5'-Amino-5'-deoxy |
| Product form | Neutral compound |
| Hydroxyl state | Free 2' and 3' hydroxyls |
| InChI | InChI=1S/C10H14N6O3/c11-1-4-6(17)7(18)10(19-4)16-3-15-5-8(12)13-2-14-9(5)16/h2-4,6-7,10,17-18H,1,11H2,(H2,12,13,14) |
| InChIKey | GVSGUDGNTHCZHI-UHFFFAOYSA-N |
| SMILES | NCC1OC(n2cnc3c(N)ncnc32)C(O)C1O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-Amino-5'-deoxyadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-Amino-5'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0092 and CAS 14365-44-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.