Modified Nucleotides
8-APT-cGMP
Quick view. We supply 8-APT-cGMP as a functionalized cyclic GMP analog for cyclic-nucleotide signaling and conjugation research. CAS 144509-87-5. Catalog target purity: ≥99%.
Product profile
8-APT-cGMP is classified as nucleotide or nucleotide analog (Formula C16H17N6O7PS; molecular weight 468.38).
8-APT-cGMP can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 8-APT-cGMP, storage: Store sealed and dry; use the lot-specific CoA for the recommended temperature and hold time.
Names and search terms
Confirmed or normalized name variants
- 8-(4-Aminophenylthio)-cGMP
- 8-p-Aminophenylthio-cGMP
- 8-APT cyclic GMP
- Sodium 6-{2-amino-8-[(2-aminophenyl)sulfanyl]-6-oxo-3,6-dihydro-9H-purin-9-yl}-7-hydroxy-2-oxotetrahydro-2H,4H-2λ⁵-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate
- 8-APT-CGMP, NA
- 8-APT-CGMP SODIUM SALT
- 8-(2-Aminophenylthio)-guanosine-3'',5''-monophosphoric acid
- 8-(2-AMINOPHENYLTHIO) GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
Useful catalog search terms
- CAS 144509-87-5
- Nucleotide or nucleotide analog
- Modified Nucleotides
Physicochemical data
| Purity basis | Research-grade target; the lot-specific CoA reports the release result and analytical method. |
|---|---|
| Functional group | 4-aminophenylthio |
| Nucleotide state | Cyclic monophosphate |
| Supply form | Dry research material |
| InChI | InChI=1S/C16H17N6O7PS.Na/c17-6-3-1-2-4-8(6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-7(28-14)5-27-30(25,26)29-11;/h1-4,7,10-11,14,23H,5,17H2,(H,25,26)(H3,18,20,21,24);/q;+1/p-1 |
| InChIKey | UGRVCFWBKAXLPC-UHFFFAOYSA-M |
| SMILES | N=c1nc([O-])c2nc(Sc3ccccc3N)n(C3OC4COP(=O)(O)OC4C3O)c2[nH]1.[Na+] |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
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Frequently asked questions
Can the package size for 8-APT-cGMP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0021 and CAS 144509-87-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry.