2'-O-Me Nucleosides
8-Chloro-2'-O-methylinosine
Quick view. 8-Chloro-2'-O-methylinosine is listed for research-use inquiry under 2'-O-Me Nucleosides. Its identity is controlled by the retained exact structure and product-form evidence because no public CAS Registry Number is assigned. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
8-Chloro-2'-O-methylinosine is classified as 2'-o-me nucleosides (Formula C11H13ClN4O5; molecular weight 316.70 g/mol).
8-Chloro-2'-O-methylinosine supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For 8-Chloro-2'-O-methylinosine, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Physicochemical data
| CAS status | No public CAS assigned |
|---|---|
| Identity control | Reviewed exact name, structure, and product form |
| InChIKey | HLDHIEUFLBFHPR-KQYNXXCUSA-N |
| InChI | InChI=1S/C11H13ClN4O5/c1-20-7-6(18)4(2-17)21-10(7)16-8-5(15-11(16)12)9(19)14-3-13-8/h3-4,6-7,10,17-18H,2H2,1H3,(H,13,14,19)/t4-,6-,7-,10-/m1/s1 |
| SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C3=C(C(=O)NC=N3)N=C2Cl)CO)O |
| Canonical SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C3=C(C(=O)NC=N3)N=C2Cl)CO)O |
| PubChem CID | 170903415 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 8-Chloro-2'-O-methylinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2-Amino-2'-O-methyladenosine
2'-O-Me Nucleosides · CAS: 80791-87-3
BX-2OMN-00032'-O-Methyl-7-deazaadenosine
2'-O-Me Nucleosides · CAS: 68345-70-0
BX-2OMN-0004N6,2'-O-Dimethyladenosine
2'-O-Me Nucleosides · CAS: 57817-83-1
BX-2OMN-00052'-O-Methylinosine
2'-O-Me Nucleosides · CAS: 3881-21-8
BX-MN-01752'-O-Methylcytidine
2'-O-Me Nucleosides · CAS: 2140-72-9
BX-MN-01782'-O-Methylguanosine
2'-O-Me Nucleosides · CAS: 2140-71-8
Frequently asked questions
Can the package size for 8-Chloro-2'-O-methylinosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMN-0151, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.