Modified Nucleosides
1-[(5E)-5,6-Dideoxy-6-phosphono-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil
Quick view. 2'-O-methyl uracil nucleoside derivative bearing an E-configured ethenylphosphonic-acid terminus. CAS 2095417-50-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
1-[(5E)-5,6-Dideoxy-6-phosphono-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil is classified as modified nucleosides (Formula C11H15N2O8P; molecular weight 334.22 g/mol).
1-[(5E)-5,6-Dideoxy-6-phosphono-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For 1-[(5E)-5,6-Dideoxy-6-phosphono-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- [(E)-2-[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]ethenyl]phosphonic acid
Useful catalog search terms
- 2095417-50-6
Physicochemical data
| Base scaffold | Uracil nucleoside |
|---|---|
| Sugar modification | 2'-O-methyl |
| Terminal group | Ethenylphosphonic acid |
| Alkene geometry | E |
| InChIKey | RLNFGWYHHIDGLE-JKXAUABFSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 1-[(5E)-5,6-Dideoxy-6-phosphono-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 1-[(5E)-5,6-Dideoxy-6-phosphono-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0817 and CAS 2095417-50-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.