Modified Nucleosides
2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine
Quick view. 2-Thiouridine derivative with both the 2'- and 3'-hydroxyl groups protected as TBDMS ethers. CAS 2305415-97-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine is classified as modified nucleosides (Formula C21H40N2O5SSi2; molecular weight 488.80 g/mol).
2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Bis-O-TBDMS-2-thiouridine
Useful catalog search terms
- 2305415-97-6
Physicochemical data
| PubChem CID | 168449893 |
|---|---|
| Nucleoside scaffold | 2-Thiouridine |
| Protecting groups | 2'-O-TBDMS; 3'-O-TBDMS |
| IUPAC name | 1-[(2R,3R,4R,5R)-3,4-bis[[tert-butyl(dimethyl)silyl]oxy]-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one |
| InChIKey | OTRKFKREBPGFCB-VDHUWJSZSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0395 and CAS 2305415-97-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.