Modified Nucleosides
2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine
Quick view. A protected uridine derivative bearing 2',3'-bis-TBDMS groups and a 4',5'-didehydro-5'-deoxy sugar unit, CAS 128070-78-0. CAS 128070-78-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine is classified as modified nucleosides (Formula C21H38N2O5Si2; molecular weight 454.71).
2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Bis-O-TBDMS-4',5'-didehydro-5'-deoxyuridine
- 2'-O,3'-O-bis(tert-butyldimethylsilyl)-4',5'-didehydro-5'-deoxyuridine
Useful catalog search terms
- CAS 128070-78-0
Physicochemical data
| Nucleobase | Uracil |
|---|---|
| Sugar modification | 4',5'-didehydro-5'-deoxy |
| Protecting groups | 2'-O-TBDMS; 3'-O-TBDMS |
| PubChem CID | 11259566 |
| InChI | InChI=1S/C21H38N2O5Si2/c1-14-16(27-29(8,9)20(2,3)4)17(28-30(10,11)21(5,6)7)18(26-14)23-13-12-15(24)22-19(23)25/h12-13,16-18H,1H2,2-11H3,(H,22,24,25)/t16-,17-,18-/m1/s1 |
| InChIKey | TYAQGUMZCVVFHL-KZNAEPCWSA-N |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](C(=C)O[C@H]1N2C=CC(=O)NC2=O)O[Si](C)(C)C(C)(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0226 and CAS 128070-78-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.