Protected Nucleosides
2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine
Quick view. A uridine derivative bearing 2'-O- and 3'-O-tert-butyldimethylsilyl groups together with 5'-O-(4,4'-dimethoxytrityl) protection, identified by CAS 82444-76-6. CAS 82444-76-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine is classified as protected nucleosides (Formula C42H58N2O8Si2; molecular weight 775.10).
2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Bis-O-TBDMS-5'-O-DMTr-uridine
Useful catalog search terms
- CAS 82444-76-6
- PubChem CID 168437207
Physicochemical data
| PubChem CID | 168437207 |
|---|---|
| InChIKey | HBLOFQAJPFGIEN-DOVDTPAYSA-N |
| Nucleoside scaffold | uridine |
| Sugar protection | 2'-O-TBDMS; 3'-O-TBDMS; 5'-O-DMTr |
| Hydroxyl state | no free ribose hydroxyl represented |
| InChI | InChI=1S/C42H58N2O8Si2/c1-40(2,3)53(9,10)51-36-34(50-38(44-27-26-35(45)43-39(44)46)37(36)52-54(11,12)41(4,5)6)28-49-42(29-16-14-13-15-17-29,30-18-22-32(47-7)23-19-30)31-20-24-33(48-8)25-21-31/h13-27,34,36-38H,28H2,1-12H3,(H,43,45,46)/t34-,36-,37-,38-/m1/s1 |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[C@H]([C@@H]1O[Si](C)(C)C(C)(C)C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0688 and CAS 82444-76-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.